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The cytoplasmic domain of CD4 is required for stable association with the lymphocyte-specific tyrosine protein kinase p56lck

✍ Scribed by André Veillette; Barry P. Sleckman; Sheldon Ratnofsky; Joseph B. Bolen; Steven J. Burakoff


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
488 KB
Volume
20
Category
Article
ISSN
0014-2980

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## cellular activation Oxford Cell surface glycoproteins anchored to the plasma membrane via glycosylphosphatidylinositol (GPI) structures, and hence having no cytoplasmic domains, can nevertheless transmit activation signals in lymphocytes. By immunoprecipitation from detergent lysates and in vit