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The cytoplasmic C-terminus of polycystin-1 increases cell proliferation in kidney epithelial cells through serum-activated and Ca2+-dependent pathway(s)

✍ Scribed by Elisa Manzati; Gianluca Aguiari; Manuela Banzi; Michele Manzati; Rita Selvatici; Sofia Falzarano; Iva Maestri; Paolo Pinton; Rosario Rizzuto; Laura del Senno

Book ID
118506005
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
1008 KB
Volume
304
Category
Article
ISSN
0014-4827

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## Abstract We investigated the effects of overexpression of the tuberous sclerosis‐1 and ‐2 (__TSC1/2__) gene products (hamartin and tuberin, respectively) in the human kidney epithelial cell line 293 with an inducible expression system. As we had observed previously in fibroblasts, 293 cells over