𝔖 Bobbio Scriptorium
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The cytodifferentiating agent SAHA inhibits prostate cancer cell growth,


Book ID
120867919
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2000
Weight
133 KB
Volume
1262
Category
Article
ISSN
1173-8324

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## Abstract Tumor suppressor genes are often silenced in human cancer; this can occur by transcriptional repression by deacetylation in the promoter regions, mediated by histone deacetylase (HDAC). HDAC inhibitors can block cancer cell growth by restoring expression of tumor suppressor genes. In th