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The cystic fibrosis transmembrane conductance regulator (CFTR) inhibits ENaC through an increase in the intracellular Cl- concentration

✍ Scribed by Konig, J.


Book ID
111744496
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
264 KB
Volume
2
Category
Article
ISSN
1469-221X

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Cystic fibrosis, the most common lethal genetic disease in the white population, is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Analysis of DNA from a pancreatic insufficient patient by chemical mismatch cleavage and subsequent DNA sequencing led to th