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The Cyclin-Dependent Kinase (CDK) Inhibitor Flavopiridol Inhibits Glycogen Phosphorylase

✍ Scribed by Astrid Kaiser; Kayoko Nishi; Fredric A. Gorin; Donal A. Walsh; E.Morton Bradbury; Joachim B. Schnier

Book ID
115568622
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
187 KB
Volume
386
Category
Article
ISSN
0003-9861

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## Abstract Roscovitine, a cyclin‐dependent kinase (Cdk) inhibitor, inhibited kinase activity and the axenic growth of __Dictyostelium discoideum__ at micromolar concentrations. Growth was almost fully rescued in 50 ¡M and ∼50% rescued in 100 ¡M roscovitine‐treated cultures by the over‐expression o