<p>During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In 1950 very little was known ofthe chemical constitution of biological systems, the manner in which information was transmitted from one organism to another, or the extent to which the ch
The Cyclic Peptide Toxins of Amanita and Other Poisonous Mushrooms
✍ Scribed by Jonathan Walton
- Publisher
- Springer International Publishing
- Year
- 2018
- Tongue
- English
- Leaves
- 253
- Edition
- 1st ed.
- Category
- Library
No coin nor oath required. For personal study only.
✦ Synopsis
Poisonous mushrooms have fascinated scientists and laypersons alike for thousands of years. Almost all mushroom fatalities are due to the genus Amanita, whose poetic common names (death cap, destroying angel) attest to their lethality. In his classic 1986 book, Theodor Wieland covered the state of our knowledge about the chemistry and biochemistry of the toxins of Amanita mushrooms up until that time, with a particular focus on the decades of chemical research by him and the Wieland dynasty (including his father, brother, brother-in-law, and cousin). Wieland’s book is now mainly of historical interest, with its exhaustive overview of the early chemical studies done without benefit of methods taken for granted by modern chemists.
This book is a complete top-to-bottom revision of Wieland’s 1986 book. The material covers history, chemistry, and biology with equal thoroughness. It should be of interest to natural products chemists and biologists, professional and amateur mycologists, and toxicologists.
The three scientific fields that are most relevant to the book are natural products chemistry, mycology, and fungal molecular genetics. Dr. Walton is an expert in all three. To maximize the broad utility and appeal of the book, care has been taken to define all technical terms specific to a particular discipline, so that, for example, mycologists will be able to understand the relevant chemistry, and chemists will be able to understand the relevant fungal biology.
✦ Table of Contents
Front Matter ....Pages i-xiii
Introduction (Jonathan Walton)....Pages 1-17
Chemistry of the Amanita Peptide Toxins (Jonathan Walton)....Pages 19-57
Distribution and Taxonomic Variation in the Amanita Cyclic Peptide Toxins (Jonathan Walton)....Pages 59-91
Biosynthesis of the Amanita Cyclic Peptide Toxins (Jonathan Walton)....Pages 93-130
Biological Activities of the Amanita Peptide Toxins (Jonathan Walton)....Pages 131-165
Ecology and Evolution of the Amanita Cyclic Peptide Toxins (Jonathan Walton)....Pages 167-204
Medical and Biotechnological Aspects (Jonathan Walton)....Pages 205-231
Future Outlook (Jonathan Walton)....Pages 233-237
Back Matter ....Pages 239-245
✦ Subjects
Life Sciences; Mycology; Plant Anatomy/Development; Plant Systematics/Taxonomy/ Biogeography; Plant Physiology; Plant Genetics and Genomics; Plant Pathology
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