## Abstract Crohn's disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBD) that are characterized by chronic intestinal inflammation and a constant influx of leukocytes mediated by proβinflammatory cytokines and chemokines. The intestinal expression of the CXCR1βbinding chem
β¦ LIBER β¦
The CXCL8/IL-8 chemokine family and its receptors in inflammatory diseases
β Scribed by Russo, Remo C; Garcia, Cristiana C; Teixeira, Mauro M; Amaral, Flavio A
- Book ID
- 121653060
- Publisher
- Expert Reviews
- Year
- 2014
- Tongue
- English
- Weight
- 856 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1744-666X
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## Abstract The threeβdimensional structure of ILβ8/CXCL8 has been previously determined using NMR spectroscopy and Xβray crystallography, but the structure of the receptors for this chemokine has not been determined experimentally. We present here the development of a model for the structure of th