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The current structural and functional understanding of APOBEC deaminases

✍ Scribed by Ronda Bransteitter; Courtney Prochnow; Xiaojiang S. Chen


Book ID
105758947
Publisher
Springer
Year
2009
Tongue
English
Weight
543 KB
Volume
66
Category
Article
ISSN
1420-682X

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✍ Bruce F. Cooper; Vera Sideraki; David K. Wilson; David Y. Dominguez; Sandra W. C πŸ“‚ Article πŸ“… 1997 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 746 KB

## Abstract For murine adenosine deaminase, we have determined that a single zinc or cobalt cofactor bound in a high affinity site is required for catalytic function while metal ions bound at an additional site(s) inhibit the enzyme. A catalytically inactive apoenzyme of murine adenosine deaminase