The cumulative irritation potential of adapalene cream and gel 0.1% compared to tazarotene creams, 0.05% and 0.1% after repeated applications to the skin of healthy subjects
✍ Scribed by Jonathan S Dosik; Stéphanie Arsonnaud
- Book ID
- 116578713
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 55 KB
- Volume
- 50
- Category
- Article
- ISSN
- 1097-6787
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A randomized, investigator masked, intra individual comparative study was conducted in 30 healthy volunteers to compare the cutaneous effects of adapalene 0.1% gel and adapalene 0.1% cream with their respective vehicles, using tretinoin 0.05% cream (n = 21) or tretinoin 0.1% cream (n = 9) and a tret
One hundred patients with acne vulgaris applied adapalene (Differin) 0.1% gel to one side of their face and tretinoin 0.025% cream to the other once a day for 4 weeks; the side of application was determined by randomization code. Patient tolerance (assessed as the side of the face least irritated by