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The CSF-FTA test and the significance of blood contamination

✍ Scribed by Dr Larry E. Davis; Sally Sperry

Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
206 KB
Volume
6
Category
Article
ISSN
0364-5134

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Although the fluorescent treponemal antibody absorption (FTA‐ABS) test has found wide application in the diagnosis of syphilis, the cerebrospinal fluid fluorescent treponemal antibody (CSF‐FTA) test is still controversial in the diagnosis of neurosyphilis. We found the CSF‐FTA test extremely sensitive to contamination with FTA‐ABS‐reactive blood at concentrations in CSF that could not be detected by visual inspection. Interpretation of a reactive test should be made with caution if red cells are present in CSF.

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