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The crystal structure of Escherichia coli class II fructose-1,6-bisphosphate aldolase in complex with phosphoglycolohydroxamate reveals details of mechanism and specificity

✍ Scribed by David R Hall; Gordon A Leonard; Christopher D Reed; C.Ian Watt; Alan Berry; William N Hunter


Book ID
115629178
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
697 KB
Volume
287
Category
Article
ISSN
0022-2836

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## Abstract Treatment of the Class II fructose‐1,6‐bisphosphate aldolase of __Escherichia coli__ with the arginine‐specific α‐dicarbonyl reagents, butanedione or phenylglyoxal, results in inactivation of the enzyme. The enzyme is protected from inactivation by the substrate, fructose 1,6‐bisphospha