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The Crystal Structure of Drosophila NLP-Core Provides Insight into Pentamer Formation and Histone Binding

✍ Scribed by V.M.Haridasan Namboodiri; Shuchismita Dutta; Ildikó V Akey; James F Head; Christopher W Akey


Book ID
114329224
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
880 KB
Volume
11
Category
Article
ISSN
0969-2126

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The crystal structure of ribonuclease A
✍ Nicolas Doucet; Thusitha B. Jayasundera; Miljan Simonović; J. Patrick Loria 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 853 KB

## Abstract Thymidine‐3′‐monophosphate (3′‐TMP) is a competitive inhibitor analogue of the 3′‐CMP and 3′‐UMP natural product inhibitors of bovine pancreatic ribonuclease A (RNase A). Isothermal titration calorimetry experiments show that 3′‐TMP binds the enzyme with a dissociation constant (__K__~d