## Abstract Recent work from our laboratory has shown that elevated src kinase activity enhances tumor promotion, malignant progression, and metastasis during multistage skin carcinogenesis. In this study, we have generated βgeneβswitchβ src^530^ transgenic mice to further analyze the role of this
β¦ LIBER β¦
The Crystal Structure of a c-Src Complex in an Active Conformation Suggests Possible Steps in c-Src Activation
β Scribed by Sandra W. Cowan-Jacob; Gabriele Fendrich; Paul W. Manley; Wolfgang Jahnke; Doriano Fabbro; Janis Liebetanz; Thomas Meyer
- Book ID
- 113918443
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 722 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0969-2126
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While the process of the Ah receptor activation leading to cytochrome P450 induction has been well studied, the mechanism and the process through which the Ah receptor activates tyrosine kinases, within a few minutes of its ligand binding, is not known. Previously, it was reported by Tannheimer et a