The Critical Role of the Constant Region in Thermal Stability and Aggregation of Amyloidogenic Immunoglobulin Light Chain
β Scribed by Klimtchuk, Elena S.; Gursky, Olga; Patel, Rupesh S.; Laporte, Kathryn L.; Connors, Lawreen H.; Skinner, Martha; Seldin, David C.
- Book ID
- 121462929
- Publisher
- American Chemical Society
- Year
- 2010
- Tongue
- English
- Weight
- 981 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0006-2960
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## Abstract IgG4 deficiency is very common (1/400 in the Italian population) and provides a good model for analyzing the genetic factors involved in Ig subclass deficiencies. We have previously reported an association between some immunoglobulin heavy chain constant region (IGHC) polymorphisms and
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