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The critical role of GRP78 in physiologic and pathologic stress

✍ Scribed by Kyle T Pfaffenbach; Amy S Lee

Book ID
113525192
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
350 KB
Volume
23
Category
Article
ISSN
0955-0674

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## Abstract As one member of 70 kDa heat shock proteins, glucose‐regulated protein 78 (GRP78) participates in protein folding, transportation and degradation. This sort of capacity can be enhanced by stresses under which GRP78 is induced rapidly. Unlike its homologues, GRP78 presents multifaceted s