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The CREB/CRE transcriptional pathway: protection against oxidative stress-mediated neuronal cell death

✍ Scribed by Boyoung Lee; Ruifeng Cao; Yun-Sik Choi; Hee-Yeon Cho; Alex D. Rhee; Cyrus K. Hah; Kari R. Hoyt; Karl Obrietan


Book ID
111181268
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
959 KB
Volume
108
Category
Article
ISSN
0022-3042

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## Abstract We examined the effects of diazoxide, the putative mitochondrial adenosine triphosphate‐sensitive potassium (mitoK~ATP~) channel opener, against glutamate excitotoxicity in primary cultures of rat cortical neurons. Cells were treated with diazoxide for 24 hr and then exposed to 200 ΞΌM g