The creatine kinase system and pleiotropic effects of creatine
β Scribed by Theo Wallimann; Malgorzata Tokarska-Schlattner; Uwe Schlattner
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 649 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0939-4451
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Covalent coupling of protein by crosslinking reagents have been used to study the interaction of mitochondrial creatine kinase (CKm) and hexokinase (HK) with the mitochondrial membranes. The effects of crosslinkers were studied either by following the inhibition of solubilization of enzymatic activi
Measurement of creatine kinase MB (CK-MB) and its isoforms CK-MB 2 and CK-MB 1 are now applied in the diagnosis of acute myocardial infarction (AMI). The most common approach for analysis includes RIA, IRMA, and electrophoresis, all of which may be time-consuming. This study examines determination o
## Abstract The structural flexibility of creatine kinase has been investigated with the covalent hydrophobic probe 2β[4β²β(2β³βiodoacetamido) phenyl] aminonaphthaleneβ6βsulfonic acid (IAANS) which reacts at vastly different rates with the two subunits to give a protein conjugate with fluorescence ch