✦ LIBER ✦
The Cram Rule Revisited Once More — Revision of the Felkin−Anh Model
✍ Scribed by Richard J. Smith; Michael Trzoss; Michael Bühl; Stefan Bienz
- Book ID
- 101350989
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 146 KB
- Volume
- 2002
- Category
- Article
- ISSN
- 1434-193X
No coin nor oath required. For personal study only.
✦ Synopsis
The reaction mechanism of the LiH addition to α-chiral ketones and acylsilanes was calculated at the ab initio MP2/6-311+G**//RHF/6-31G* level. The selectivities predicted on the basis of the computed transition states and reaction barriers compare well with the experimental data. For compounds possessing very large groups, anti-Cram selectivity