The Coxsackie-adenovirus receptor has elevated expression in human breast cancer
β Scribed by T. A. Martin; G. Watkins; W. G. Jiang
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 146 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0372-8722
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## Abstract ## Background Adenoviral vectors are widely used as geneβtransfer vehicles in experimental and clinical studies. Since virus incorporation and transfection efficacy depend to a large extent on the concentration of the coxsackieβandβadenovirus (CAR) receptor on target cells the aim of t
## Abstract The sensitivity of human tissues and tumors to infection with type C adenoviruses correlates with the expression of the human coxsackie Bβ and adenovirus receptor, hCAR. HCAR is heterogeneously expressed in various tissues and types of human cancer cells, which has implications for the