mcl-1 was identified as an "early-induction" gene that increases in expression during the differentiation of ML-1 human myeloblastic leukemia cells. The mcl-1 gene product proved to be a member of the bcl-2 gene family and, like bcl-2, to have the capacity to promote cell viability. The pattern of e
โฆ LIBER โฆ
THE COUPLING OF VINCULIN TO THE CYTOSKELETON IS NOT ESSENTIAL FOR MECHANO-CHEMICAL SIGNALING IN F9 CELLS
โ Scribed by Wolfgang H Goldmann
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 136 KB
- Volume
- 26
- Category
- Article
- ISSN
- 1065-6995
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The signaling mechanisms leading to phorbol ester myristate (PMA)-induced differentiation of HL-60 cells to the macrophagelike phenotype were investigated by using different protein kinase inhibitors. The protein kinase C inhibitor Ro 31-8220 specifically blocks PMA-induced differentiation, activati