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The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

โœ Scribed by Paterson, Alison M; Mitsdoerffer, Meike; Ho, I-Cheng; Sharpe, Arlene H; Kuchroo, Vijay K; Bauquet, Aurelie T; Jin, Hulin


Book ID
109920749
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
684 KB
Volume
10
Category
Article
ISSN
1529-2908

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The recent discovery and characterization of T helper 17 cells (Th17) and their signature cytokines (IL-17) represents a hallmark in T-cell immunobiology by providing a new distinctive pathway for the communication between adaptive and innate immunity. From the six members of the IL-17 cytokine fami