The cooperative effect of electrostatic and hydrophobic forces in the complexation of cationic molecules by a water-soluble resorcin[4]arene derivative

✍ Scribed by Seong Jin Park; Jong-In Hong

• Publisher: Elsevier Science
• Year: 2000
• Tongue: French
• Weight: 105 KB
• Volume: 41
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)01441-6

✦ Synopsis

A new water-soluble resorcin [4]arene derivative 4 was synthesized and the complexation of cationic guests in D 2 O was studied by 1 H NMR spectroscopy. A 1:1 binding mode was elucidated by a Job's plot. The cooperative effect of electrostatic and hydrophobic interactions acts as a binding force for a strong complex formation with appropriate cationic guests in water. The thermodynamic parameters of complexation of guest I determined by a van't Hoff plot indicate that the complexation process is both enthalpically and entropically driven.