The Cooperative Effect in Ion-Pair Recognition by a Ditopic Hemicryptophane Host

Chiral separation machinery using new cr

Chiral separation machinery using new crystalline inclusion hosts: Match/mismatch in the enantiomer recognition of (R,S)-1-methoxy-2-propanol effected by a borneol/fenchol building block exchange in the host molecule

✍ Mátyás Czugler; Petros P. Korkas; Petra Bombicz; Wilhelm Seichter; Edwin Weber 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 258 KB 👁 3 views

New chiral host molecules 1 and 2 involving a bulky terpenoid unit and aromatic ethyne spacer groups were synthesized using Pd-catalyzed cross-coupling reactions of (+)-2␣-ethynyl-2␤-hydroxybornane (4) or (+)-2␣-ethynyl-2␤-hydroxyfenchane (5) with 9,10-dibromoanthracene. Host compounds 1 and 2 form