During embryogenesis and in the early stages of life, the thymus is a crucial organ for the generation of the T cell repertoire. T cells are generated from hematopoietic stem cells already differentiated to precursor T cells in the bone marrow. These cells enter the thymus guided by chemotactic fact
The contribution of stressful life events throughout the life cycle to combat-induced psychopathology
β Scribed by Zahava Solomon; Shlomit Zur-Noah; Danny Horesh; Gadi Zerach; Giora Keinan
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 164 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0894-9867
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β¦ Synopsis
Abstract
This study examines the contribution of prewar life events, war exposure, and postwar life events to combatβinduced psychopathology among 425 Israeli War veterans from the Lebanon War. Data was collected at two time points (1983 and 2002). The sample included veterans with and without combat stress reaction (CSR). Battle intensity and subjective experience of risk in war were associated with CSR. Negative childhood life events, CSR, PTSD in 1983 and postwar negative life events were associated with PTSD in 2002. Furthermore, a path analysis revealed that CSR mediated the relation between battle intensity and PTSD in 2002. Our findings suggest that stressful life events throughout the life cycle contribute significantly to veterans' posttraumatic symptomatology, above and beyond combat exposure.
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Cluster analysis was used to categorize stressful life events into groups based on the effect (or mediational) pattern linking each event to external criteria defined within an overarching conceptual model. To illustrate the utility of "effect size clustering," we examined the structure of stressful