The contribution of senescing dermal fibroblasts to the phenotype observed in aging skin
β Scribed by Wang, CK; Kutzkey, T; Funk, W; Pagon, G; Hoeffler, WK
- Book ID
- 119562424
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 177 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0923-1811
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
In this study we investigated the influence of keratinocytes on the phenotype of fibroblasts in an in vitro human skin equivalent. Keratinocytes were seeded at the surface of fibroblast-populated mechanically restrained type I collagen gels (lattices). Lattices without keratinocytes were handled in
EPC-1 (early population doubling level cDNA-1) is a quiescence-specific gene expressed at high levels by early passage WI-38 fibroblasts under conditions of either density-dependent growth arrest or serum deprivation. Late passage WI-38 cells lose the ability to express EPC-1 under all conditions te