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The contribution of inherited genotype to breast cancer

โœ Scribed by Timothy R Rebbeck


Book ID
120700918
Publisher
BioMed Central
Year
2002
Tongue
English
Weight
77 KB
Volume
4
Category
Article
ISSN
1465-5411

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A total of 283 epithelial ovarian cancer families from the United Kingdom (UK) and the United States (US) were screened for coding sequence changes and large genomic alterations (rearrangements and deletions) in the BRCA1 and BRCA2 genes. Deleterious BRCA1 mutations were identified in 104 families (