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The contribution of HLA to multiple sclerosis susceptibility in Sardinian affected sibling pairs

✍ Scribed by Maria Giovanna Marrosu; Elisabetta Fadda; Cristina Mancosu; Marina Lai; Eleonora Cocco; Maura Pugliatti


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
917 KB
Volume
47
Category
Article
ISSN
0364-5134

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Analysis of HLA haplotype distributions in relation to major affective disorder in affected sibling pairs and affected aunt or uncle and niece or nephew pairs confirmed that HLA-region genes do contribute to susceptiblity to affective disorder. The data indicated that this effect may be greater in u