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The Contribution of Calpains in the Down-regulation of Mdm2 and p53 Proteolysis in Reconstructed Human Epidermis in Response to Solar Irradiation

✍ Scribed by Christelle Gélis; Alain Mavon; Patricia Vicendo


Book ID
111412944
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
957 KB
Volume
81
Category
Article
ISSN
0031-8655

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Atherosclerosis is a fibroproliferative disease of the arterial intima. It was recently found that wild-type p53 (wt p53) accumulates in human atherosclerotic tissue. Wt p53 is a cell cycle regulator involved in DNA repair, DNA synthesis, cell differentiation, and apoptosis and might therefore make