𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The constitution of hypoglycin B

✍ Scribed by C.H. Hassall; D.I. John


Publisher
Elsevier Science
Year
1959
Tongue
French
Weight
81 KB
Volume
1
Category
Article
ISSN
0040-4039

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✦ Synopsis


IN a recent publication rL there is evidence supporting the formulation of hypoglycin B2 as the dipeptfde Y-L-glut~lO~~no-~-(2-met~lenecyclopropyl) propionic acid (I). This is baeed on hydrolysis experiments on the peptide and its Z,&dinitrophenyl-derivative, together with the indication by Ven Slyke amino-nitrogen snd oarboxyl determinations that the glutamic acid residue is attached by a Y-link. We have been led independently, by similar evidence, to the same conclusion concerning the


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## Abstract The dipeptide hypoglycin B, one of two toxins of the ackee fruit (__Blighia sapida__ Koenig), was characterized for the first time by NMR spectral data, which led to the discovery that it exists naturally as a pair of diastereomers. No distinction was observed in the ^1^H NMR signals of