## Abstract CXCR4 is a chemokine receptor implicated in the homing of cancer cells to target metastatic organs, which overexpress its ligand, stromal cellβderived factor (SDF)β1. To determine the efficacy of targeting CXCR4 on primary tumor growth and metastasis, we used a peptide inhibitor of CXCR
β¦ LIBER β¦
The conjugation of RGDS peptide with CM-chitin augments the peptide-mediated inhibition of tumor metastasis
β Scribed by Hiroyuki Komazawa; Ikuo Saiki; Yu Igarashi; Ichiro Azuma; Seiichi Tokura; Masayoshi Kojima; Atsushi Orikasa; Mitsunori Ono; Isamu Itoh
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 810 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0144-8617
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## Abstract The anti Herβ2/neu monoclonal antibody Trastuzumab has strong inhibiting effects on tumor growth __in vitro__ and __in vivo__ and is therefore used for immunotherapy in breast cancer patients. Due to necessity of frequent applications, however, cost intensiveness of Trastuzumab treatmen