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The conformational alteration of the mutated extracellular domain of Fas in an adult T cell leukemia cell line

โœ Scribed by Takahiro Maeda; Susumu Nakayama; Yasuaki Yamada; Kazuyuki Sugahara; Hajime Isomoto; Masayuki Tawara; Reishi Yamasaki; Yasuyuki Onimaru; Tetsuro Matsushita; Yoshiyuki Ohzono; Shimeru Kamihira


Book ID
117052454
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
333 KB
Volume
296
Category
Article
ISSN
0006-291X

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โœ Kazuyuki Sugahara; Yasuaki Yamada; Youichi Hiragata; Yuzi Matsuo; Kazuto Tsuruda ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 78 KB ๐Ÿ‘ 2 views

Fas, also designated as Apo-1 and CD95, is a cell membrane receptor (mFas) involved in apoptotic cell death. A soluble form (sFas) lacking the transmembrane domain due to alternative splicing has been isolated. Abnormal expression of sFas and mFas is likely to be involved in lymphoproliferative diso