The excision repair of DNA damaged by physical or chemical agents may produce either apurinic/apyrimidinic (AP) sites or single-strand breaks (SSB) in the DNA. Alkaline-sucrose gradient sedimentation and alkaline elution, techniques generally used for the study of DNA repair which depend upon high p
The conformation of single-strand polynucleotides in solution: sedimentation studies of apurinic acid
β Scribed by Eugene K. Achter; Gary Kelsenfeld
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1971
- Tongue
- English
- Weight
- 641 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0006-3525
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The conformation and the dynamic structure of single-stranded poly(U) and poly(C) in neutral aqueous solution have been investigated by 'H-nmr at two different frequencies (90 and 250 MHz) and at various temperatures. Measurements of proton chemical shifts, coupling constants JH-H, and proton relaxa