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The conduct of a two-generation reproductive toxicity study via dermal exposure in the Sprague-Dawley rat—a case study with KBR 3023 (a prospective insect repellent)

✍ Scribed by A.B. Astroff; K.J. Freshwater; A.D. Young; B.P. Stuart; G.K. Sangha; J.H. Thyssen


Book ID
114274250
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
168 KB
Volume
13
Category
Article
ISSN
0890-6238

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✍ Astroff, A.B.; Young, A.D.; Holzum, B.; Sangha, G.K.; Thyssen, J.H. 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 107 KB 👁 1 views

KBR 3023, 1-(1-methyl-propoxycarbonyl)-2-(2-hydroxyethyl)piperidine, a prospective insect repellent being developed by Bayer Corporation, was evaluated for developmental toxicity in the Sprague-Dawley rat and Himalayan rabbit. As the intended human usage of the test compound is topical, the test sys