Induction of the cytoplasmic petite mutation in yeast by 5-fluorouracil (5FU) and 5-fluorocytosine (5FC) is known to depend on the incorporation of 5FU into some species of RNA; 5FC is active only following deamination to 5FU. Several mutants ahve now been isolated which are resistant to petite muta
โฆ LIBER โฆ
The conditions required for the induction of petite yeast mutants by fluorinated pyrimidines
โ Scribed by Oliver, Stephen G. ;Williamson, Donald H.
- Publisher
- Springer
- Year
- 1976
- Tongue
- English
- Weight
- 689 KB
- Volume
- 146
- Category
- Article
- ISSN
- 0026-8925
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Sequence analysis was used to define the repeat unit that constitutes the mitochondrial genome of a petite (rho-) mutant of the yeast Saccharomyces cerevisiae. This mutant has retained and amplified in tandem a 2,547 bp segment encompassing the second exon of the oxi3 gene excised from wild-type mtD