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The Concomitant Use of Dystrophin and Utrophin/Dystrophin Related Protein Antibodies to Reduce Misdiagnosis of Duchenne/Becker Muscular Dystrophy

✍ Scribed by Tejvir S. Khurana; Linda A. Specht; Alan H. Beggs; Fernando M.S. Tomé; France Letureq; Martine Chevallay; Philippe Chafey; Louis M. Kunkel


Book ID
115581306
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
567 KB
Volume
241
Category
Article
ISSN
0006-291X

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Pattern of deletions of the dystrophin g
✍ Coral-Vázquez, Ramón; Arenas, Diego; Cisneros, Bulmaro; Peñaloza, Laura; Salaman 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 416 KB 👁 3 views

We have analyzed 59 unrelated Mexican Duchenne/Becker muscular dystrophy patients (DMD/BMD) using PCR analysis of the 2 prone deletion regions in the DMD gene. Thirty one (52%) of the patients had a deletion of one or several of the exons. Most of the alterations (87%) were clustered in exons 44-52,