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The concept of a random coil: Residual structure in peptides and denatured proteins

✍ Scribed by Lorna J. Smith; Klaus M. Fiebig; Harald Schwalbe; Christopher M. Dobson


Book ID
114382584
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
494 KB
Volume
1
Category
Article
ISSN
1359-0278

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An important problem in protein folding is to understand the relationship between the structure of a denatured ensemble and its thermodynamics. Using 0 -6M GdnHCl at fixed pH, we evaluated dimensional changes of an extensively denatured ensemble along with a thermodynamic parameter (⌬) that monitors