The Computer Simulation of RNA Folding Pathways Using a Genetic Algorithm
โ Scribed by Alexander P. Gultyaev; F.H.D. van Batenburg; Cornelis W.A. Pleij
- Book ID
- 115627042
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 710 KB
- Volume
- 250
- Category
- Article
- ISSN
- 0022-2836
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๐ SIMILAR VOLUMES
We have developed a novel Hill-climbing genetic algorithm (GA) for simulation of protein folding. The program (written in C) builds a set of Cartesian points to represent an unfolded polypeptide's backbone. The dihedral angles determining the chain's configuration are stored in an array of chromosom
Ab-initio folding simulations have been performed on three small proteins using a genetic algorithm-(GA-) based search method which operates on an all atom representation. Simulations were also performed on a number of small peptides expected to be independent folding units. The present genetic algo