β Scribed by Ronald A. Bergman PhD, Paul M. Heidger Jr. PhD, Carol E. H. Scott-Conner MD,PhD (auth.), Anthony J. Bowdler MD, PhD, FRCPLOND, FRCPATH, FACP (eds.)
No coin nor oath required. For personal study only.
Since the publication of The Complete Spleen: Structure, Function, and Clinical Disorders under the title of The Spleen in 1990, there has appeared a wealth of new information that now demands incorporation into the diagnosis and management of patients with splenic disorders. In this 2nd edition, an international panel of distinguished clinical and scientific investigators has thoroughly revised and updated Professor Anthony Bowdler's classic work, emphasizing those functions principally reserved to the spleen, especially the spleen's microvasculature, uniquely adapted to particle filtration, and the consequent mechanisms of its immune responses.
Among the disease aspects critically surveyed in rich detail are the causes of splenic enlargement, the meaning of hypersplenism, hyposplenism and its causes and management, and the unusual cytopenias that accompany the disorders of the spleen, including those caused by maldistribution and dilutional anemias. Diseases given focused attention include the myelo- and lymphoproliferative disorders, hemolytic diseases, and the sickle-cell disorders. These are followed by details of the radiological examination of the spleen, of the present status of surgical intervention, with emphasis on tissue and functional conservation, and of the recently developed laparoscopic methods.
Comprehensive and state-of-the-art, The Complete Spleen: Structure, Function, and Clinical Disorders makes available to all physicians and clinical researchers a coherent account of today's dramatically more detailed knowledge of the spleen and its unique functions as part of the immune system, as well as our optimal current strategies for the management of its pathologies.
Front Matter....Pages i-xviii
Front Matter....Pages 1-1
The Anatomy of the Spleen....Pages 3-9
The Microanatomy of the Mammalian Spleen....Pages 11-21
Splenic Microcirculatory Blood Flow and Function with Respect to Red Blood Cells....Pages 23-50
The Immune Functions of the Spleen....Pages 51-69
The Role of the Spleen in Hemostasis....Pages 71-75
Front Matter....Pages 77-N4
The Pathology of the Spleen....Pages 79-105
Splenic Pooling and Survival of Blood Cells....Pages 107-121
Dilutional Anemia....Pages 123-135
Front Matter....Pages 137-137
The Clinical Significance of the Spleen....Pages 139-155
Hyposplenism....Pages 157-173
The Relationship of the Spleen to Infection....Pages 175-191
Hemolysis and Thrombocytopenia....Pages 193-212
Myeloproliferative Disorders....Pages 213-221
The Spleen in Lymphoproliferative Disease....Pages 223-250
The Spleen in Sickle Cell Disease....Pages 251-257
Imaging of Spleen Disorders....Pages 259-280
Surgery of the Spleen....Pages 281-313
Back Matter....Pages 315-331
Gastroenterology
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