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The complete genome sequence of a dog: a perspective

✍ Scribed by Soohyun Lee; Simon Kasif


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
81 KB
Volume
28
Category
Article
ISSN
0265-9247

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✦ Synopsis


Abstract

A complete, high‐quality reference sequence of a dog genome was recently produced by a team of researchers led by the Broad Institute, achieving another major milestone in deciphering the genomic landscape of mammalian organisms. The genome sequence provides an indispensable resource for comparative analysis and novel insights into dog and human evolution and history. Together with the survey sequence of a poodle previously published in 2003, the two dog genome sequences allowed identification of more than 2.5 million single nucleotide polymorphisms within and between dog breeds, which can be used in evolutionary analysis, behavioral studies and disease gene mapping.1 Β© 2005 Wiley Periodicals, Inc. BioEssays 28: 569–573, 2006. Β© 2006 Wiley Periodicals, Inc.


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