The complement system in rheumatoid synovitis i. an analysis of complement component activities in rheumatoid synovial fluids
โ Scribed by Dr. Shaun Ruddy; K. Frank Austen
- Publisher
- John Wiley and Sons
- Year
- 1970
- Tongue
- English
- Weight
- 682 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0004-3591
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โฆ Synopsis
Abstract
Stoichiometric hemolytic assays were used to measure the activities of the first four reacting components of the complement sequence in synovial fluids from patients with seropositive or seronegative rheumatoid arthritis or degenerative joint disease. The pattern of component reductions in the seropositive rheumatoid arthritis fluids was consistent with activation of the complement system by an intraโarticular immunologic process.
๐ SIMILAR VOLUMES
## Abstract Analyses of CH50, complement components, properdin factors, and kininogen in synovial fluid of patients with juvenile rheumatoid arthritis revealed evidence of activation of the classic complement pathway in all clinical subgroups. Juveniles with the adult pattern of disease had the gre