The combined effects of bleomycin and sulfhydryl compounds on the thermal denaturation of DNA
β Scribed by Kazuo Nagai; Hiroshi Yamaki; Hideo Suzuki; Nobuo Tanaka; Hamao Umezawa
- Book ID
- 115743428
- Publisher
- Elsevier Science
- Year
- 1969
- Weight
- 437 KB
- Volume
- 179
- Category
- Article
- ISSN
- 0005-2787
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## Abstract DNA thermal denaturation has been investigated in aqueous solutions of diethylsulfoxide (DESO) by means of UVβvis and densimetry methods. It is suggested that, on the one hand, the structural change of entire solutions and, on the other hand, a direct interaction of DESO with DNA are re
When DNA's of differing GC:AT base ratios, e.g. synthetic poly dAT, T4 DNA, calf thymus DNA, E. coli DNA, and M. lysodeikticus DNA, are heat-denatured a t neutral pH in increasing concentrations of N&SO4 or CsZSO4 as supporting electrolytes, the variation of melting temperature with average base com