The combination of lead with a protein kinase C inhibitor causes oxidative stress in human neuroblastoma cells

MIBG causes oxidative stress and up-regu

MIBG causes oxidative stress and up-regulation of anti-oxidant enzymes in the human neuroblastoma cell line SK-N-BE(2C)

✍ Jan Cornelissen; André B.P. Van Kuilenburg; P.A. Voûte; Albert H. Van Gennip 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 97 KB 👁 2 views

We report the effects of meta-iodobenzylguanidine (MIBG), a neuroblastoma-seeking agent, on cell proliferation and several oxidative stress-related parameters in the human neuroblastoma cell line SK-N-BE(2c). MIBG inhibited the proliferation of this cell line in micromolar concentrations. Measuremen