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The Colon Cancer Burden of Genetically Defined Hereditary Nonpolyposis Colon Cancer

✍ Scribed by Wade S. Samowitz; Karen Curtin; Heather H. Lin; Margaret A. Robertson; Donna Schaffer; Melanie Nichols; Kristen Gruenthal; Mark F. Leppert; Martha L. Slattery

Book ID
119756359
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
199 KB
Volume
121
Category
Article
ISSN
0016-5085

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✍ Henry T. Lynch; Thomas Smyrk; Jeremy R. Jass πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 688 KB

Hereditary nonpolyposis colorectal cancer (HNPCC) results from an inherited defect in one of the genes responsible for repair of errors that occur during DNA replication. Affected individuals have high risk for cancers of the colon and certain extracolonic sites. It appears that HNPCC patients form