✦ LIBER ✦

The Coincidence of Schizophrenia and Idiopathic Parkinson's Disease: Successful Treatment with a Combination of Antiparkinsonian Drugs and Atypical Antipsychotic Drugs

✍ Scribed by MASAYUKI WATANABE; YOSHIO KODAMA; KUNIO SHIMIZU; NAOMICHI ICHINOWATARI

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 110 KB
Volume: 12
Category: Article
ISSN: 0885-6222
DOI: 10.1002/(sici)1099-1077(199705/06)12:3<271::aid-hup861>3.0.co;2-f

No coin nor oath required. For personal study only.

✦ Synopsis

It is rare for schizophrenia and idiopathic Parkinson's disease to occur in the same patient. This report describes a case in which a chronic schizophrenic patient later developed idiopathic Parkinson's disease. Both the psychotic and the parkinsonian symptoms of the patient were well controlled with the combination of antiparkinson drugs (bromocriptine and L-threo-DOPS) and atypical antipsychotic drugs (sulpiride and thioridazine). It is suggested that excessive dopaminergic activity in the mesolimbic system may coexist with dopaminergic de®ciency in the nigrostriatal system in this patient.

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