𝔖 Bobbio Scriptorium
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The coin toss of B cells in rejection and tolerance: Danger versus defense

✍ Scribed by Valeriya Zarkhin; Minnie M. Sarwal

Book ID
116885713
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
869 KB
Volume
24
Category
Article
ISSN
1044-5323

No coin nor oath required. For personal study only.

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## Abstract Steady‐state dendritic cells (DC) present peptide‐MHC complexes to T cells in a tolerogenic manner, presumably because of deficient costimulation. However, it is clear that the path to tolerance involves initial T cell activation, suggesting that the deficit may lie in late‐acting costi