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The codon adaptation index-a measure of directional synonymous codon usage bias, and its potential applications

✍ Scribed by Sharp, Paul M.; Li, Wen-Hsiung

Book ID
118071098
Publisher
Oxford University Press
Year
1987
Tongue
English
Weight
969 KB
Volume
15
Category
Article
ISSN
0305-1048

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The codon adaptation index-a measure of
The codon adaptation index-a measure of directional synonymous codon usage bias, and its potential applications
✍ Sharp, Paul M.; Li, Wen-Hsiung 📂 Article 📅 1987 🏛 Oxford University Press 🌐 English ⚖ 969 KB

A simple, effective measure of synonymous codon usage bias, the Codon Adaptation Index, is detailed. The index uses a reference set of highly expressed genes from a species to assess the relative merits of each codon, and a score for a gene is calculated from the frequency of use of all codons in th