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The cochlear F-box protein OCP1 associates with OCP2 and connexin 26

✍ Scribed by Michael T. Henzl; Isolde Thalmann; John D. Larson; Elena G. Ignatova; Ruediger Thalmann


Book ID
116524546
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
320 KB
Volume
191
Category
Article
ISSN
0378-5955

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Hereditary hearing loss (HHL) is one of the most common congenital disorders and is highly heterogeneous. Mutations in the connexin 26 (CX26) gene (GJB2) account for about 20% of all cases of childhood deafness, and approach 50% in documented recessive cases of non-syndromic hearing loss. In additio