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The coagulation defect in the L5222 experimental rat leukemia

✍ Scribed by Herbert Rasche; Dieter Hoelzer; Manfred Dietrich; Eberhard Kurrle; Horst Pflieger

Book ID
113237863
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
134 KB
Volume
1
Category
Article
ISSN
0145-2126

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## Abstract An experimental model of meningeal leukemia in rats is developed by intracerebral (IC) inoculation of leukemic cells from the transplantable acute leukemia L5222. The L5222 proliferates exponentially in the central nervous system (CNS) and the disease becomes systemic 2 days following I