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The CO2 content of the gastric mucosa

โœ Scribed by Irving, Laurence ;Wilson, M. J.

Publisher
Wiley (John Wiley & Sons)
Year
1932
Tongue
English
Weight
389 KB
Volume
2
Category
Article
ISSN
0095-9898

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โœฆ Synopsis

The gastric mucosa is remarkable for its ability to secrete strong hydrochloric acid in relatively large amounts. The problem of considering the process is in some respects more difficult than that which is involved in the concentration or dilution of a secretion, for passage of water by osmotic forces is often a satisfactory physiological hypothesis. But in the gastric mucosa the strong hydrochloric acid is derived from the neutral chlorides of the blood and is discharged in considerable quantity at pH near one.

Another view of the problem raises the question as to how the mucosa itself can survive the constant contact of the strongly acid juice. In order to allow for protection of the mucosa, it is only necessary to postulate that it is imperme-

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