The cloning of cholesterol 7 α-hydroxylase: Will molecular techniques help us understand the physiology of bile acid synthesis?

Regulation of bile acid synthesis by deo

Regulation of bile acid synthesis by deoxycholic acid in the rat: Different effects on cholesterol 7α-hydroxylase and sterol 27-hydroxylase

✍ Sarah Shefer; Betsy T. Kren; Gerald Salen; Clifford J. Steer; Lien B. Nguyen; Th 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 982 KB

We examined the effects of feeding deoxycholic acid (1% and 0.4% of diet), alone and in combination with ursodeoxycholic acid, on serum and biliary bile acid concentrations, hepatic morphology, and the activities and steady-state messenger RNA (mRNA) levels of HMG-CoA reductase and cholesterol 7a-hy